The director commented that Nagai's later works were "even more extreme" and so he created Crybaby with the mindset of "If Nagai-sensei could have done as he pleased, he'd have gone this far".  Because of that, some episodes feature extended rap sequences performed by professional rappers.
 The Devilmen running-style attracted some attention among anime fans, including YouTuber PewDiePie, and was dubbed "the best animated running since Naruto". The character of Mico, from the original manga, is split into two characters within the series- one is Miki "Miko" Kuroda and the other is an unnamed character who makes a cameo appearance in the last episode. Devilman Crybaby is based on Go Nagai's manga Devilman.  It features commentaries done through rapid text messages and social media to explore humans' reaction to demons.  The Decider's Eric Thurm said the mass violence reflects the anti-war narrative and that the series' "political message" is a reflection on "humanity's tendency toward paranoia and willingness to turn on others".  Gamespot's Kaille Plagge described it as a meditation on the meaning of being human, while Lynzee Loveridge of Anime News Network wrote it questions whether or not there is a line that separates humanity from monstrosity.  Toole stated it is "the most ludicrously violent, sexed-up anime TV series ever aired", while Joyce Slaton wrote for Common Sense Media that its mature content exceed what is expected to be featured in adult-aimed anime.  The complete box also included a Devilman Crybaby Freestyle Rap All Tracks CD.  Toole said that at first Devilman Crybaby appears to be "a straight take on Nagai's classic story", and also compared the first episodes to the 1987 original video animation of Devilman.
, Think of the story as a relay race where tears are passed as a baton.  Inoa wrote that the "immediate reaction" to it indicated it was probably Yuasa's most popular work. Weak and unassuming, Akira Fudou has always had a bleeding heart. Opposites attract at Christmas as cynical Dash and sunny Lily trade messages and dares in a red notebook they pass back and forth around New York City. She is now half Caucasian, along with Taro.  Nagai himself, the 1970s Devilman anime screenwriter Masaki Tsuji, and filmmaker Sion Sono praised Crybaby.
Miki's father searches for his missing wife and son. , Many critics commented about "the remarkable animation style", as reported Pementel.  The way it dealt with sexuality and its openly LGBT characters also received praise; Surat said "many strongly resonate with Crybaby for its emphasis on explicitly gay and lesbian characters in a dramatic presentation".  Crybaby was also chosen among the best anime of the 2010s by the staffs of Polygon and Crunchyroll, while Paste magazine's staff elected it the 35th best anime of all time, with critic Toussaint Egan writing the anime is "not only as one of the best series in recent memory, but one that will stand the test of time".  It turned out to be "the first big talking point of the year in the anime community", according to Syfy.com's Christopher Inoa.  Toole commented that Crybaby discusses the proliferation of urban legends and the difficulty people have to deal with "societal upheaval".  Its two-disc, 48-track original soundtrack was released on January 10, 2018, by Aniplex. After taking to social media to defend Akira, Miki and her friends are violently murdered by a paranoid mob who believes them to be demons. Ryo films the demons massacring the humans but is attacked and pinned by a demon. The anti-war themes of the manga are present but passed over to focus more on the xenophobia and racism angle instead. Akira kills the mob in retribution after witnessing them parading around with the dismembered bodies of his friends on sticks. Studio This project also marks Go Nagai's 50th year as a creator. With the fear of demons gripping the world, humanity devolves into paranoia and violence. Devilman Wiki is a FANDOM Anime Community. Ichirō Ōkouchi
Several characters from the manga including Demon General.
Confronted by Akira, Ryo reveals the truth about demonkind and himself.
Akira and Ryo's friendship becomes strained overtime due to Ryo's extreme actions to protect Akira's secret.  Likewise, Sam Reach of Anime News Network commented, "Go Nagai fever is running red-hot nowadays, thanks in no small part to Devilman Crybaby".